| Target antigen: |
HOXA11 |
| Clonality: |
Polyclonal antibody |
| Clone: |
Polyclonal antibody |
| Raised in: |
rabbit |
| Type of the antibody: |
IgG polyclonal antibody |
| Product form: |
freeze-dried |
| Reacts with species:: |
human, rat |
| Analyses: |
WB |
| Immunogen: |
E.coli-derived human HOXA11 recombinant protein (Position: H74-R245). Human HOXA11 shares 95% amino acid (aa) sequence identity with mouse HOXA11. |
| Product configuration: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Purification: |
Immunogen affinity purified. |
| Solubilization: |
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml |
| Storage condtions: |
Keep the HOXA11 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way. |
| Tips: |
The HOXA11 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics. |
| Background: |
Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene. It is mapped to 7p15.2. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is involved in the regulation of uterine development and is required for female fertility. HOXA11 is essential for the development of the uterosacral ligaments, it has been found that women with pelvic organ prolapse may have weakened connective tissue due to changes in this signaling pathway. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. |
| Related articles: |
1. McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. 2. Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. 3. "Entrez Gene: HOXA11 homeobox A11" |
| Gene Name: |
HOXA11 |
| Protein Name: |
Homeobox protein Hox-A11 |
| Gene Full Name: |
homeobox A11 |
| Synonyms: |
Homeo box 1I antibody|Homeo box A11 antibody|Homeobox A11 antibody|Homeobox protein Hox A11 antibody|Homeobox protein Hox-1I antibody|Homeobox protein Hox-A11 antibody|Homeobox protein HOXA11 antibody|Hox 1I antibody|Hox-1I antibody|HOX1 antibody|HOX1I antibody|HOXA11 antibody|HXA11_HUMAN antibody |
| Uniprot ID: |
P31270 |
| Entrez GeneID: |
3207 |
| Properties: |
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation: |
anticorps |