| Target antigen: |
HOXA3 |
| Clonality: |
Polyclonal antibody |
| Clone: |
Polyclonal antibody |
| Raised in: |
rabbit |
| Type of the antibody: |
IgG polyclonal antibody |
| Product form: |
freeze-dried |
| Reacts with species:: |
human, mouse Predicted to work with: rat |
| Analyses: |
WB,IHC-P |
| Immunogen: |
A synthetic peptide corresponding to a sequence at the C-terminus of human HOXA3(427-443aa HHPSQGRIQEAPKLTHL), identical to the related rat and mouse sequences. |
| Product configuration: |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Purification: |
Immunogen affinity purified. |
| Solubilization: |
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml |
| Storage condtions: |
Keep the HOXA3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way. |
| Tips: |
The HOXA3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics. |
| Background: |
HOXA3(HOMEOBOX A3) is a protein that in humans is encoded by the HOXA3 gene, which is also part of the A cluster on chromosome 7. HOXA3 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 protein is able to complement Hoxd3 deficiency when expressed in the context of the Hoxd3 allele. |
| Related articles: |
1. Greer, J. M., Puetz, J., Thomas, K. R., Capecchi, M. R. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 403: 661-665, 2000. 2. McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". 3. Han L, Witmer PD, Casey E, Valle D, Sukumar S (2007). "DNA methylation regulates MicroRNA expression". |
| Gene Name: |
HOXA3 |
| Protein Name: |
Homeobox protein Hox-A3 |
| Gene Full Name: |
homeobox A3 |
| Synonyms: |
Homeo box 1E antibody|Homeo box A3 antibody|Homeobox 1E antibody|Homeobox A3 antibody|Homeobox protein HOX A3 antibody|Homeobox protein Hox-1E antibody|Homeobox protein Hox-A3 antibody|Homeobox protein HOXA3 antibody|Homeobox1E antibody|HomeoboxA3 antibody|HOX 1 antibody|Hox 1.5 like protein antibody|HOX 1E antibody|HOX A3 antibody|HOX1 antibody|Hox1.5 antibody|Hox1.5 like protein antibody|HOX1E antibody|HOXA 3 antibody|HOXA3 antibody|HXA3_HUMAN antibody|MGC10155 antibody |
| Uniprot ID: |
O43365 |
| Properties: |
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation: |
anticorps |