| Category: |
Antibody |
| Concentration: |
0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HOXA1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur. |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 0.5-1ug/ml |
| Notes: |
The stated application concentrations are suggested starting amounts. Titration of the HOXA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Intented use: |
This HOXA1 antibodyis to be used only for research purposes and not for diagnostics.. |
| Uniprot #: |
P49639 |
| Purity: |
Antigen affinity |
| Description: |
HOXA1 (HOMEOBOX A1), also called HOMEOBOX 1F, is a protein that in humans is encoded by the HOXA1 gene. In PA-1 teratocarcinoma cells, HOXA1 was induced by retinoic acid earlier than other HOXA cluster genes. The HOXA1 gene is mapped on 7p15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. A common polymorphism in the HOXA1 gene is associated with a susceptibility to autism spectrum disorder. Three-dimensional reconstructions of Hoxa1 -/- rhombencephalon revealed that it bears only 5 rhombomeric structures instead of the normal 7. A single maternal administration of a low dose of the vitamin A metabolite retinoic acid was sufficient to compensate the requirement for Hoxa1 function in Hoxa1-deficient mice. |
| Immunogen: |
An amino acid sequence from the N-terminus of human HOXA1(MDNARMNSFLEYPIL) was used as the immunogen for this HOXA1 antibody (100% mouse homology). |
| Storage: |
After reconstitution, the HOXA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing. |
| Properties: |
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation: |
anticorps |